TYPE 2 DIABETES AND OBESITY RESEARCH TOOLS AND ONLINE RESOURCES
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JAX® Mice Database
- The most comprehensive source of genotypic and phenotypic data on JAX® Mice strains
- Detailed information on more than 200 JAX® Mice models for diabetes and obesity
- Offers capability to search for mouse models of disease using human OMIM terms
TALLYHO/JNGJ RESPONSE TO ROSIGLITAZONE
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Figure 1. Rosiglitazone at 3mg/kg had no effect, but 30mg/kg progressively lowered fed blood glucose.
PHENOTYPE INFORMATION FOR B6-DB (000697)
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Type 2 diabetes phenotypes in male and female C57BL/6J mice with the leptin receptor mutation (B6-db; B6.BKS(D)-Leprdb/J) include:
PHENOTYPE INFORMATION FOR BKS-DB (000642)
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Male and female C57BLKS/J mice with the leptin receptor mutation (BKS-db; BKS.Cg-Dock7m +/+ Leprdb/J) develop type 2 diabetes with phenotypes that include:
PHENOTYPE INFORMATION FOR 004456
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NONcNZO10/LtJ
NONcNZO10/LtJ (also known as RCS-10) males develop maturity-onset diabetes without the extreme weight gain characteristic of other models.
PHENOTYPE INFORMATION FOR B6-OB (000632)
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Type 2 diabetes phenotypes in male and female C57BL/6J leptin mutant mice (B6-ob; B6.Cg-Lepob/J) include:
FEATURED JAX® MICE MODELS OF TYPE 2 DIABETES & OBESITY
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Name & Stock Number PHENOTYPE COMPARISONS FOR TOP METABOLIC MODELS.content-div{padding:0px 60px 0px 60px;}
CHOOSING & MAINTAINING MICE FOR TYPE 2 DIABETES AND OBESITY RESEARCH.content-div{padding:0px 60px 0px 60px;}
To choose the most appropriate model(s) for type 2 diabetes and obesity research, many factors need to be considered, including the following:
COMPARISON OF WIDELY USED JAX MICE FOR TYPE 2 DIABETES AND OBESITY.content-div{padding:0px 60px 0px 60px;}
Diabetes Phenotypes
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