JAX^® Mice Database

• The most comprehensive source of genotypic and phenotypic data on JAX^® Mice strains
• Detailed information on more than 200 JAX^® Mice models for diabetes and obesity
• Offers capability to search for mouse models of disease using human OMIM terms

Mouse Phenome Database

• Houses baseline phenotypic and genotypic data on commonly used and genetically diverse inbred mouse strains
• Includes baseline phenotypes for normal and diet-induced changes in plasma phospholipids, lipids, lipoprotein, glucose, and hormone levels, body weight, body composition, bone mineral density, and susceptibility to disease
• Phenotypes characterized by strain and sex
• Raw data can be downloaded, manipulated, and analyzed with database tools
• Fully integrated with the Mouse Genome Informatics (MGI) database

Mouse Genome Informatics

• Provides integrated access to data on the genetics, genomics, and biology of the laboratory mouse
• Captures data on mutant genotypes and phenotypes of all types, including spontaneous, chemically- and radiation-induced, and other genetically engineered mutations (transgenic, targeted, conditional, etc.)
• Offers cross species comparisons

Choosing & maintaining mice for type 2 diabetes and obesity research

Factors to consider when choosing models and tips for maintaining obese mice.

Animal Models of Diabetic Complications Consortium

• Provides phenotypic data and resources on mouse models of diabetes complications
• Primary goal is to construct animal models for studying diabetes-complication pathologies, with an emphasis on etiology, prevention, and treatment
• Consists of eight Mouse Engineering and Phenotyping units from different institutions and one Coordinating and Bioinformatics unit
• Members are scientists who have expertise in mouse genetic engineering technologies, organ pathologies, genomic technologies, and diabetic complications