Let In Vivo Pharmacology Services at JAX perform your lupus-related efficacy study using robust systemic lupus erythematosus (SLE) mouse models

Defective immune tolerance causes SLE in males and females of this thoroughly characterized lupus model

Detailed phenotypes of the MRL-lpr lupus model

SLE develops in males due to a Y-linked mutation that dysregulates immune signaling

Abnormal immune responses underlie a SLE model with a female bias seen in the human disease